You should try to give yourself at least an hour every day to work on your highest priority tasks. It is best if you can have a quiet, uninterrupted work time allowing you to concentrate. Set the time at a point in the day where you are at your most alert and effective. Arrange to have a secretary or colleague take your calls. If this is not possible, you can close your door and activate your voice mail. As an alternative, take the time at home or another location, where you will not be interrupted.